Sign in →

Test Code ADAMS ADAMTS13 Activity Assay, Plasma


Ordering Guidance


Consider ordering in patients with known diagnosis of congenital, immune, or acquired thrombotic thrombocytopenic purpura.



Specimen Required


Patient Preparation: Fasting preferred

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vials

Specimen Volume: 2 mL in 2 plastic vials each containing 1 mL

Collection Instructions:

1. Specimen must be collected prior to replacement therapy.

2. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.

3. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.

4. Aliquot plasma (1 mL per aliquot) into 2 separate plastic vials, leaving 0.25 mL in the bottom of centrifuged vial.

5. Freeze plasma immediately (no longer than 4 hours after collection) at -20° C or, ideally, below -40° C.

Specimen Stability Information: Frozen 2 years

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. Each coagulation assay requested should have its own vial.


Useful For

Assisting with the diagnosis and monitoring of congenital, immune, or acquired thrombotic thrombocytopenic purpura

Method Name

Fluorescence Resonance Energy Transfer (FRET)

Reporting Name

ADAMTS13 Activity Assay, P

Specimen Type

Plasma Na Cit

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen

Reference Values

≥70%

Although not verified, the pediatric (<1 years old) reference range could be similar to or lower than that of adults.

Day(s) Performed

Monday through Friday, Sunday

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

85397

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ADAMS ADAMTS13 Activity Assay, P 53622-7

 

Result ID Test Result Name Result LOINC Value
620816 ADAMTS13 Activity 53622-7
620819 Interpretation 69049-5

Forms

If not ordering electronically, complete, print, and send one of the following with the specimen:

-Renal Diagnostics Test Request (T830)

-Coagulation Test Request (T753)