Test Code ARSU Arylsulfatase A, 24 Hour, Urine
Reporting Name
Arylsulfatase A, UUseful For
Detection of arylsulfatase A deficiency using urine specimens
This test is not suitable for carrier detection.
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
UrineOrdering Guidance
The preferred test to rule-out metachromatic leukodystrophy is ARSAW / Arylsulfatase A, Leukocytes.
Shipping Instructions
Specimen must be received at least 1 day prior to assay day for processing.
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL tube
Specimen Volume: 6 mL
Collection Instructions:
1. Collect a 24-hour urine specimen.
2. No preservative.
3. Refrigerate specimen during collection.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Specimen Minimum Volume
2.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated | 14 days |
Special Instructions
Reference Values
≥19 nmol/h/mL
Note: Results from this assay may not reflect carrier status because of individual variation of arylsulfatase A enzyme levels. Low normal values may be due to the presence of pseudodeficiency or carrier alleles. Patients with these depressed levels may be phenotypically normal.
Day(s) Performed
Tuesday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84311
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ARSU | Arylsulfatase A, U | 42726-0 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8777 | Arylsulfatase A, U | 42726-0 |
37423 | Interpretation (ARSU) | 59462-2 |
37413 | Reviewed By | 18771-6 |
Report Available
9 to 16 daysMethod Name
Colorimetric, Enzyme Assay
Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Biochemical Genetics Patient Information (T602)
3. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.
Testing Algorithm
See Lysosomal Storage Disorders Diagnostic Algorithm, Part 2