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HelpTest Code LAB23 Digoxin, Plasma or Serum
Reporting Title
Digoxin
Methodology
Roche Diagnostics, Electrochemiluminescence Immunoassay- RMH, GMC, DH, DMH, GMH, WECC, PMC, GCMH, BH, OBH, MGH, MH, HMH, SH
Digoxin is prescribed for treatment of congestive heart failure and cardiac rhythm disturbances.
Performing Laboratory
OhioHealth Laboratory Services- RMH,GMC, DH, DMH, MGH, GMH, HMH, WECC, PMC, OBH, MH, SH, GCMH, BH Core Laboratories
Specimen Requirements
Collection Instructions:
1. Serum and Plasma gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.
Due to interference, patients receiving high doses of biotin (>5 mg/day) should wait at least 8 hours after dose before having blood drawn.
Submit only 1 of the following specimens:
Preferred:
Serum
Draw blood in a gold-top or a speckled-top serum gel tube(s). Spin down and send 1 mL of serum refrigerated. Specimen for a trough level should be drawn 8 hours after completion of infusion of an intravenous dose or 12 hours after an oral dose.
Note: 1. Plain, red-top tube(s) is also acceptable.
2. Patients receiving therapy with mouse monoclonal antibodies may have erroneous results.
3. Indicate serum on request form.
4. Label specimen appropriately (serum).
Alternate:
Plasma
Draw blood in a mint green-top (heparin) gel tube(s). Spin down and send 1 mL of heparinized plasma refrigerated. Specimen for a trough level should be drawn 8 hours after completion of infusion of an intravenous dose or 12 hours after an oral dose.
Note: 1. Patients receiving therapy with mouse monoclonal antibodies may have erroneous results.
2. Indicate plasma on request form.
3. Label specimen appropriately (plasma).
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum or plasma | Refrigerated | 14 days |
| Ambient | 7 days | |
| Frozen | 6 months |
Specimen Transport Temperature
Refrigerate/Ambient/Frozen ok
Reference Values
Therapeutic concentration: 0.5-2.2 ng/mL
Critical value >2.5 ng/mL
Alerting category: Always called within 1 hour
Note: 1. Digoxin-like immunoreactive substances have been identified in patients with renal or liver failure and third trimester pregnancy. These may cause falsely elevated results.
2. Patients receiving Digoxin Immune FAb will have erroneous results.
3. DigibindTM, digitoxin, digoxigenin, nabumetone, and uzara may cause falsely elevated results.
Day(s) Test Set Up
Monday through Sunday; Continuously
Test Classification and CPT Coding
80162