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Test Code LAB28 Gentamicin, Peak/Post-Dose, Plasma or Serum

Additional Codes

45689

Reporting Title

Gentamicin Post-Dose

Methodology

Roche Diagnostics 

Siemens Diagnostics- OMH and MH

Gentamicin has a narrow therapeutic index and an unpredictable dose-serum profile curve.

Performing Laboratory

OhioHealth Laboratory Services-RMH, GMC, OMH, MH Core Laboratory

Specimen Requirements

Collection Instructions:

1. Serum and Plasma gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

Submit only 1 of the following specimens:

 

Preferred:

Serum

Draw blood in a gold-top serum gel tube(s) 60 minutes after an intravenous infusion (intravenous piggyback [IVPB] conventional dosing). Spin down and send 1 mL of serum refrigerated.

Note:

1. Date and time of draw are required on request form and specimen for processing.

2. A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable.

3. Indicate serum and peak/post-dose on request form.

4. Label specimen appropriately (serum and as peak/post-dose).

 

Alternate: Preferred by Siemens Users

Plasma

Draw blood in a mint green-top (heparin) gel tube(s) 60 minutes after an intravenous infusion (intravenous piggyback [IVPB] conventional dosing). Spin down and send 1 mL of heparinized plasma refrigerated.

Note:  1. Date and time of draw are required on request form and specimen for processing.

2. Indicate plasma and peak/post-dose on request form.

3. Label specimen appropriately (plasma and as peak/post-dose).

 

Sample Stability Information:

Specimens removed from the cells, clot, or gel may be stored up to one week at 2 to 8°C.

If testing will be delayed more than one week, specimens should be stored frozen (< -10°C).

 

Specimen Transport Temperature

Refrigerate/Frozen OK/Ambient NO

Reference Values

Therapeutic range:  5.0-10.0 mcg/mL

Critical value  >12.0 mcg/mL

Alerting category: Always called within 1 hour

Note:  Sagamicin, sisomycin, and netilmicin interfere with this assay. Concurrent treatment with other nephrotoxic drugs may increase nephrotoxicity.

Day(s) Test Set Up

Monday through Sunday; Continuously

Test Classification and CPT Coding

80170