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Test Code LAB313 D-Dimer, Blood or Plasma

Reporting Title

D-Dimer

Methodology

Diagnostica Stago, Inc

Used to screen for the detection of deep vein thrombosis (DVT), evaluate acute myocardial infarction, and unstable angina.

Performing Laboratory

OhioHealth Laboratory Services- RMH, GMC, DH, DMH, MGH, GMH, HMH, GCMH, MH, SH, BH, PMC, WECC and OMH Core Laboratories

Specimen Requirements

Submit only 1 of the following specimens:

Draw a full, light blue-top (citrate) tube; and send citrated whole blood. Invert several times to mix blood. Forward unprocessed whole blood promptly at ambient temperature only. Do not refrigerate. 

Note: 1. This assay requires its own specimen.

2. Gross hemolysis, icterus, and lipemia may affect results.

3. Indicate whole blood on request form.

4. Label specimen appropriately (whole blood).

Specimen Stability Information

Specimen Type Temperature Time
Unspun whole blood Room Temperature 8 hours 
Spun, capped whole blood Room Temperature 8 hours 
  Refrigerate Do not refrigerate

 

Outpatients/Outreach Clients (when testing is not able to be performed on whole blood within 8 hours, send frozen plasma)

Plasma-Frozen

Draw a full, light blue-top (citrate) tube. Spin down, remove plasma, spin plasma again, and place 1 mL of citrated platelet-poor plasma into a plastic vial. (Glass vial is not acceptable.) Pour-off vial should be no more than 2/3 full. Send specimen frozen.

 

Note: 1. This assay requires its own specimen.

2. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious

    results.

3. Gross hemolysis, icterus, and lipemia may affect results.

4. Indicate plasma on request form.

5. Label specimen appropriately (plasma).

 

 

Specimen Transport Temperature

Whole Blood: Ambient Yes / Refrigerate NO / Frozen NO

Citrated Plasma  Frozen Yes /Refrigerate NO/Ambient NO

Reference Values

Reference range: 0.27-0.49 mcg/mL FEU

Cutoff of <0.5 mcg/mL FEU is considered low probability for pulmonary embolism and/or DVT.

Any value ≥0.5 mcg/mL FEU suggests the need for further clinical investigation.

D-Dimer determinations should always be evaluated in conjunction with clinical and other laboratory findings. Lipemic specimens can lead to falsely elevated or decreased values.

Day(s) Test Set Up

Monday through Sunday; Continuously

Test Classification and CPT Coding

85379