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Test Code LAB366 Immunoglobulin Total Light Chains, Urine

Additional Codes

Mayo Test ID
TLCU

48360

Reporting Name

Immunoglobulin Total Light Chains,U

Useful For

Monitoring patients whose urine demonstrates large M-spikes

 

Confirming the quantitation of specimens that show M-spikes by electrophoresis

 

Detecting urine monoclonal proteins and identification of specimens that need urine protein electrophoresis

Profile Information

Test ID Reporting Name Available Separately Always Performed
KTLCU Kappa Total Light Chain, U No Yes
LTLCU Lambda Total Light Chain, U No Yes
KLTRU Kappa/Lambda TLC Ratio, U No Yes

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


If serum is being submitted on the same patient for FLCS / Immunoglobulin Free Light Chains, Serum; that test should be ordered under a different order number.



Specimen Required


Submit only 1 of the following specimens:

Supplies:  Sarstedt Aliquot Tube, 5 mL (T914)

 

Specimen Type: Random urine

Collection Container/Tube: Clean, plastic urine collection container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 1 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Refrigerate after collection and send refrigerate.

 

Specimen Type: 24-Hour urine

Container/Tube: Plastic, 5-mL tube

Specimen Volume: 1 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. No additive needed for preservation.

3. Urine may be kept ambient during the collection period but should be refrigerated within 4 hours of collection completion.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Frozen  20 days
  Ambient  72 hours

Reference Values

KAPPA TOTAL LIGHT CHAIN

<0.9 mg/dL

 

LAMBDA TOTAL LIGHT CHAIN

<0.7 mg/dL

 

KAPPA/LAMBDA RATIO

0.7-6.2

Day(s) Performed

Monday through Friday

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83883 x 2

OhioHealth Laboratory Services Note:

83521 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TLCU Immunoglobulin Total Light Chains,U 44792-0

 

Result ID Test Result Name Result LOINC Value
KLTRU Kappa/Lambda TLC Ratio, U 33559-6
KTLCU Kappa Total Light Chain, U 27365-6
LTLCU Lambda Total Light Chain, U 27394-6

Report Available

Same day/1 to 3 days

Method Name

KTLCU, LTLCU: Nephelometry

Urine Preservative Collection Options

Note: The application of temperature controls must occur within 4 hours of completion of the collection.

Ambient (No additive)

OK <72 hours

Refrigerate (No additive)

Preferred

Frozen (No additive)

OK

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No