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Test Code LAB43 Acetaminophen, Plasma or Serum

Additional Codes

ACTM

Reporting Title

Acetaminophen

Methodology

Roche Diagnostics - RMH, BH, DH, DMH, GCMH, GMC, GMH, MGH, MH, OBH, PMH, WECC, HMH, SH

Acetaminophen overdose can cause hepatotoxicity and nephrotoxicity.

Performing Laboratory

OhioHealth Laboratory Services - RMH, BH, DH, DMH, GCMH, GMC, GMH, HMH, MGH, MH, OBH, PMC, SH, WECC Core Laboratories

Specimen Requirements

Submit only 1 of the following specimens:

 

Preferred:

Serum

Draw blood in a gold-top serum gel tube(s). Spin down and send 1 mL of serum refrigerated. Avoid hemolysis.
Note:

1. A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable.

2. Indicate serum on request form.

3. Label specimen appropriately (serum).

 

Alternate: Preferred for Siemens Users

Plasma

Draw blood in a mint green-top (heparin) gel tube(s). Spin down and send 1 mL of heparinized plasma refrigerated. Avoid hemolysis.

Note:  1. Indicate plasma on request form.

2. Label specimen appropriately (plasma).

 

Specimen Stability Information

Specimen Type Temperature Time
Serum or plasma Refrigerated 7 days capped
  Ambient  24 hours capped
  Frozen  6 months capped

 

Specimen Transport Temperature

Refrigerate/Ambient NO/Frozen OK

Reference Values

Therapeutic concentration:  10-30 mcg/mL

Critical values  >50 mcg/mL

Alerting category: Always called within 1 hour

 

Toxic level, potentially toxic at:

>200 mcg/mL (4 hours post dose)

>100 mcg/mL (8 hours post dose)

>50 mcg/mL (12 hours post dose)

The level at which toxicity occurs decreases with increasing half-lives until it is encountered at values as low as 50 mcg/mL when the half-life is 12 hours. Amitriptyline and imipramine falsely lower test results.

Day(s) Test Set Up

Monday through Sunday; Continuously

Test Classification and CPT Coding

80143