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Test Code LAB43 Acetaminophen, Plasma or Serum

Additional Codes

45014

ACTM

Reporting Title

Acetaminophen

Methodology

Roche Diagnostics RMH,GMC,DH,DMH, GMH, WECC,PMC, GCMH

Siemens Diagnostics  MGH, HMH, MH, SH and OBL

Acetaminophen overdose can cause hepatotoxicity and nephrotoxicity.

Performing Laboratory

OhioHealth Laboratory Services-RMH,GMC,DH,DMH, MGH, GMH, HMH, OMH, MH, SH, WECC, PMC, GCMH Core Laboratories

Specimen Requirements

Submit only 1 of the following specimens:

 

Preferred:

Serum

Draw blood in a gold-top serum gel tube(s). Spin down and send 1 mL of serum refrigerated. Avoid hemolysis.
Note:

1. A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable.

2. Indicate serum on request form.

3. Label specimen appropriately (serum).

 

Alternate: Preferred for Siemens Users

Plasma

Draw blood in a mint green-top (heparin) gel tube(s). Spin down and send 1 mL of heparinized plasma refrigerated. Avoid hemolysis.

Note:  1. Indicate plasma on request form.

2. Label specimen appropriately (plasma).

 

Specimen Stability Information

Specimen Type Temperature Time
Serum or plasma Refrigerated 7 days capped
  Ambient  24 hours capped
  Frozen  6 months capped

 

Specimen Transport Temperature

Refrigerate/Ambient NO/Frozen OK

Reference Values

Therapeutic concentration:  10-30 mcg/mL

Critical values  >50 mcg/mL

Alerting category: Always called within 1 hour

 

Toxic level, potentially toxic at:

>200 mcg/mL (4 hours post dose)

>100 mcg/mL (8 hours post dose)

>50 mcg/mL (12 hours post dose)

The level at which toxicity occurs decreases with increasing half-lives until it is encountered at values as low as 50 mcg/mL when the half-life is 12 hours. Amitriptyline and imipramine falsely lower test results.

Day(s) Test Set Up

Monday through Sunday; Continuously

Test Classification and CPT Coding

80329

G0480