Test Code LAB43 Acetaminophen, Plasma or Serum
Additional Codes
ACTM
Reporting Title
Acetaminophen
Methodology
Roche Diagnostics - RMH, BH, DH, DMH, GCMH, GMC, GMH, MGH, MH, OBH, PMH, WECC, HMH, SH
Acetaminophen overdose can cause hepatotoxicity and nephrotoxicity.
Performing Laboratory
OhioHealth Laboratory Services - RMH, BH, DH, DMH, GCMH, GMC, GMH, HMH, MGH, MH, OBH, PMC, SH, WECC Core Laboratories
Specimen Requirements
Submit only 1 of the following specimens:
Preferred:
Serum
Draw blood in a gold-top serum gel tube(s). Spin down and send 1 mL of serum refrigerated. Avoid hemolysis.
Note:
1. A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable.
2. Indicate serum on request form.
3. Label specimen appropriately (serum).
Alternate: Preferred for Siemens Users
Plasma
Draw blood in a mint green-top (heparin) gel tube(s). Spin down and send 1 mL of heparinized plasma refrigerated. Avoid hemolysis.
Note: 1. Indicate plasma on request form.
2. Label specimen appropriately (plasma).
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Serum or plasma | Refrigerated | 7 days capped |
Ambient | 24 hours capped | |
Frozen | 6 months capped |
Specimen Transport Temperature
Refrigerate/Ambient NO/Frozen OK
Reference Values
Therapeutic concentration: 10-30 mcg/mL
Critical values >50 mcg/mL
Alerting category: Always called within 1 hour
Toxic level, potentially toxic at:
>200 mcg/mL (4 hours post dose)
>100 mcg/mL (8 hours post dose)
>50 mcg/mL (12 hours post dose)
The level at which toxicity occurs decreases with increasing half-lives until it is encountered at values as low as 50 mcg/mL when the half-life is 12 hours. Amitriptyline and imipramine falsely lower test results.
Day(s) Test Set Up
Monday through Sunday; Continuously
Test Classification and CPT Coding
80143