Test Code LAB468 Diazepam and Metabolites, Serum
Additional Codes
Mayo Test ID |
---|
DIA |
45452
Reporting Name
Diazepam and metabolites, SUseful For
Assessing compliance
Monitoring for appropriate therapeutic level
Assessing diazepam toxicity
Performing Laboratory

Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Serum Red | Refrigerated (preferred) | 28 days |
Ambient | 28 days | |
Frozen | 28 days |
Reference Values
Therapeutic concentrations
Diazepam: Not established
Diazepam and Nordiazepam: 100-2,500 ng/mL
Cutoff concentrations by liquid chromatography tandem mass spectrometry:
Diazepam: 10 ng/mL
Nordiazepam: 10 ng/mL
Oxazepam: 10 ng/mL
Temazepam: 10 ng/mL
Day(s) Performed
Wednesday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
DIA | Diazepam and metabolites, S | 49044-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8629 | Diazepam | 3548-5 |
2475 | Nordiazepam | 3537-8 |
2459 | Diazepam and Nordiazepam | 16757-7 |
622868 | Oxazepam | 3886-9 |
622869 | Temazepam | 10343-2 |
Report Available
3 to 7 daysMethod Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.