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Test Code LAB491 Protein S Activity, Functional, Blood or Plasma

Important Note

Please see the Coagulation Limitations under resources for effect of Anticoagulant drugs in this test.

Additional Codes

47630

Reporting Title

Protein S Activity (Functional)

Methodology

Diagnostica Stago Inc.

Used to detect protein S deficiencies.

Performing Laboratory

OhioHealth Laboratory Services-RMH Core Coagulation

Specimen Requirements

Riverside Inpatient or Riverside Campus draw sites:

Testing must be performed within 4 hours of draw if submitting unprocessed whole blood.

 

Draw 2 full, light blue-top (citrate) tube; and send citrated whole blood. Invert several times to mix blood. Forward unprocessed whole blood promptly at ambient temperature only. Do not refrigerate.

Note:  1. This assay requires its own specimen.

2. Gross hemolysis, icterus, and lipemia may affect results.

3. Indicate whole blood on request form.

4. Label specimen appropriately (whole blood).

 

Outpatient/Outreach Clients

Plasma

Draw 2 full, light blue-top (citrate) tube. Spin down, remove plasma, spin plasma again, and place 1 mL of citrated platelet-poor plasma into 2 plastic vials each containing 1.0 mL.  plastic vial. (Glass vial is not acceptable.) Pour-off vials should be no more than 2/3 full. Send specimen frozen.

Note:   1. This assay requires its own specimen.

2. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

3. Gross hemolysis, icterus, and lipemia may affect results.

4. Indicate plasma on request form.

5. Label specimen appropriately (plasma).

 NOTE: Two aliquots required due to possible reflex to Protein S Antigen (Free and Total)

 

Specimen Transport Temperature

Ambient/Refrigerate NO/Frozen NO-Blood

Frozen/Refrigerate NO/Ambient NO-Plasma

Reference Values

51-131%

Results <51% will reflex a protein S free antigen assay

Note:  The presence of heparin >1.2 U/mL or lupus-type anticoagulants may cause falsely elevated results.

Day(s) Test Set Up

Monday and Wednesday

Test Classification and CPT Coding

85306