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HelpTest Code LAB66 Creatinine, Plasma or Serum
Reporting Title
Creatinine
Methodology
These methods have been standardized against ID-MS.
Roche Diagnostics, Jaffe Kinetic Alkaline Picrate at RMH, GMC, DH, DMH, GMH, WECC, PMC, DHC, GCMH, BH, OBH, MGH, HMH, SH
Note: Hemoglobin F interferes with this method. We recommend that a whole blood creatinine be run on infants through the first year of life.
Creatinine is normally excreted by glomerular filtration. It is useful in diagnosing and monitoring acute and chronic renal disease and in monitoring dialysis.
VWH Lab Only:
CREA reagent, when used in conjunction with UniCel® DxC 860i System(s) and SYNCHRON® Systems Multi Calibrator, is intended for the quantitative determination of Creatinine concentration in human serum, plasma or urine.
Performing Laboratory
OhioHealth Laboratory Services-RMH, GMC, DH, DMH, WECC, PMH, DHC, MGH, GMH, HMH, OBH, MH, SH, GCMH, BH and VWH Core Laboratories
Specimen Requirements
Collection Instructions:
1. Serum and Plasma gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.
Submit only 1 of the following specimens:
Preferred:
Serum
Draw blood in a gold-top serum gel tube(s). Spin down and send 1 mL of serum refrigerated.
Note:
1. A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable.
2. Indicate serum on request form.
3. Label specimen appropriately (serum).
Alternate preferred for VWH Lab:
Plasma
Draw blood in a mint green-top (heparin) gel tube(s). Spin down and send 1 mL of heparinized plasma refrigerated.
Note:
1. Indicate plasma on request form.
2. Label specimen appropriately (plasma).
VWH Lab:
3. Tubes of blood are to be kept closed at all times and in a vertical position. It is recommended that the serum or plasma be physically separated from contact with cells within two hours from the time of collection.
4. Separated serum or plasma should not remain at room temperature longer than 8 hours. If assays are not completed within 8 hours, serum or plasma should be stored at +2°C to +8°C. Refrigerated samples are stable for 48 hrs.
Roche Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum or plasma | Refrigerated | 7 days |
| Ambient | 7 days | |
| Frozen | 3 months |
Specimen Transport Temperature
Refrigerate/Ambient OK/Frozen OK
Reference Values
Males
0-5 days: 0.3-1.0 mg/dL
6-30 days: 0.3-0.7 mg/dL
31 days-1 year: 0.2-0.4 mg/dL
2-12 years: 0.3-0.7 mg/dL
13-18 years: 0.5-1.0 mg/dL
19-60 years: 0.5-1.3 mg/dL
61-90 years: 0.8-1.3 mg/dL
>91 years: 1.0-1.7 mg/dL
Critical value >9.0 mg/dL
Alerting category: First instance called within 1 hour
Females
0-5 days: 0.3-1.0 mg/dL
6-30 days: 0.3-0.7 mg/dL
31 days-1 year: 0.2-0.4 mg/dL
2-12 years: 0.3-0.7 mg/dL
13-18 years: 0.5-1.0 mg/dL
19-60 years: 0.4-1.1 mg/dL
61-90 years: 0.6-1.2 mg/dL
>91 years: 0.6-1.3 mg/dL
Critical value >9.0 mg/dL
Alerting category: First instance called within 1 hour
VWH Lab:
Serum or Plasma (Male): 0.4 – 1.1 mg/dL
Day(s) Test Set Up
Monday through Sunday; Continuously
Test Classification and CPT Coding
82565