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HelpTest Code LAB852 Extractable Nuclear Antigen Antibodies, Serum
Reporting Title
ENA Screen 7
Methodology
| Reflex Tests: | ||
| Unit Codes | Published Name | Available Separately |
|
LAB2001 |
Autoantibodies to Sm/Autoantibodies to RNP |
Yes |
| LAB344 | Autoantibodies to Ro56/Ro60/SS-A/Autoantibodies to SS-B/La | Yes |
| LAB771 | Autoantibodies to Scl 70 | Yes |
| LAB770 | Autoantibodies to Jo 1 | Yes |
Testing Algorithm:
If antibodies to extractable nuclear antigens (ENA) are positive, Jo 1, Scl 70, Sm/RNP, Ro52, Ro60 and SS-B/La are performed.
Method Name:
BIO-FLASH Chemiluminescent Immunoassay
General Information:
Identification of antibodies to ENA is useful in detection, diagnosis, and differentiation of connective tissue diseases, such as systemic lupus erythematosus and Sjögren’s syndrome.
Performing Laboratory
OhioHealth Laboratory Services-RMH Special Testing
Specimen Requirements
Draw blood in a gold-top serum gel tube(s). (Hemolyzed, icteric, microbially contaminated or heat-treated specimens are not acceptable). Spin down and send 1 mL of serum refrigerated. Sample is stable refrigerated for 7 days
Note: A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable.
Specimen Transport Temperature
Refrigerate: OK
Frozen: OK
Reference Values
Negative
Day(s) Test Set Up
Monday through Friday day shift only
Test Classification and CPT Coding
86235 - screen, negative result
86235 x 8 - positive result (screen and antibodies to Sm,RNP, Ro52, Ro60, SS-B/La, Scl 70, Jo 1) (if appropriate)