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Test Code LAB858 Thyroperoxidase (TPO) Antibodies, Plasma or Serum

Reporting Title

Thyroid Peroxidase Antibody

Methodology

Beckman Coulter DxI® 800 Immunoassay System

Useful in diagnosis of thyroid autoimmune disease such as Grave’s or Hashimoto’s disease. Thyroid Microsomal Antibody has been shown to be the same as TPO.

Performing Laboratory

OhioHealth Laboratory Services-RMH Special Testing

Specimen Requirements

Hemolyzed and lipemic samples are not acceptable.

 

Submit only 1 of the following specimens:

 

Preferred:

Serum

Draw blood in a gold-top serum gel tube(s). Spin down immediately and send 1 mL of serum refrigerated.
Note:

1. A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable..

2. TPO autoantibodies may be found in <10% of population and in patients with non-thyroid disease such as inflammatory rheumatic diseases.

3. Heterophile antibodies may interfere with this assay.

4. Indicate serum on request form.

5. Label specimen appropriately (serum).

 

Alternate:

Plasma

Draw blood in a mint green-top (heparin) gel tube(s) or a lavender-top (EDTA) tube(s). Spin down immediately and send 1 mL of heparinized or EDTA plasma refrigerated.

Note:  1. TPO autoantibodies may be found in <10% of population and in patients with non-thyroid disease such as inflammatory rheumatic diseases.

2. Heterophile antibodies may interfere with this assay.

3. Indicate plasma on request form.

4. Label specimen appropriately (plasma).

 

Specimen Stability Information

Specimen Type Temperature Time
Serum and Plasma Refrigerated 6 days
  Ambient  24 hours
  Frozen  Stable

 

Specimen Transport Temperature

Refrigerate/Ambient OK/Frozen OK

Reference Values

0-9.0 IU/mL

Day(s) Test Set Up

Monday through Friday day shift only

Test Classification and CPT Coding

86376