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Test Code LAB90112 Epstein-Barr Virus (EBV) Screen

Reporting Title

EBV Screen

Methodology

Profile Information:
Unit Codes Published Name Available Separately
     
 LAB793 Epstein-Barr Nuclear Antigen (EBNA) Yes 
   LAB1730 Epstein-Barr Viral Capsid Antigen (VCA), IgG Yes
   LAB1731 Epstein-Barr Viral Capsid Antigen (VCA), IgM Yes
 LAB654 Epstein-Barr Virus (EBV) IgG Antibody to Early Antigen Yes

Qualitative results of EBV antibodies aid in diagnosis of infectious mononucleosis. The presence of VCA IgG antibodies indicate a past infection with EBV. The presence of VCA IgM antibodies indicate a primary recent infection with EBV. EBNA antibodies develop 6 to 8 weeks after primary infection. Epstein-Barr virus early antigen (EBVEA) indicates that EBV is actively replicating. Over 90% of the normal adult population have antibodies to VCA IgG and EBNA.

Note:  Of patients with nasopharyngeal carcinoma, type 2 and 3, 94% and 83% respectively, have positive antibody response to EBVEA.

Performing Laboratory

OhioHealth Laboratory Services-RMH Special Testing

Specimen Requirements

Draw blood in a gold-top serum gel tube(s). (Contaminated, hemolyzed, or icteric specimen is not acceptable.) Spin down and send 1 mL of serum refrigerated.

Note:  A speckled-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable.

 

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated 2 days
  Ambient   
  Frozen  Stable

 

Specimen Transport Temperature

Refrigerate/Ambient OK/Frozen OK

Reference Values

See individual test listings.

Day(s) Test Set Up

Monday through Friday Continuous

Saturday and Sunday Day shift only

Test Classification and CPT Coding

86663 - EBV early antigen

86664 - EBNA

86665 x 2 - VCA, IgG and IgM