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Test Code LAB90263 Sex Hormone binding Globulin, S

Important Note

For SHBG pediatric samples (males <20 and females <21), a miscellaneous test should be ordered with SHBG listed in the comments. This can be serum from a red top tube. Minimum sample volume is 0.5mL.

Additional Codes


Reporting Title

Sex Hormone Binding Globulin, S


Roche Diagnostics Electrodhemiluminescence Immunoassay

Diagnosis and follow-up of women with symptoms or signs of androgen excess (eg, polycystic ovarian syndrome and idiopathic hirsutism)

An adjunct in monitoring sex-steroid and anti-androgen therapy

An adjunct in the diagnosis of disorders of puberty

An adjunct in the diagnosis and follow-up of anorexia nervosa

An adjunct in the diagnosis of thyrotoxicosis (tissue marker of thyroid hormone excess)

A possible adjunct in diagnosis and follow-up of insulin resistance and cardiovascular and type 2 diabetes risk assessment, particularly in women.

Specimen Transport Temperature

Ambient OK/Refrigerated OK/Frozen OK

Test Classification and CPT Coding


Reference Values


20-49 years:     16.5-55.9 nmol/L

≥ 50 years:      19.3-76.4 nmol/L


21-49 years:        24.6-122 nmol/L

≥50 years           17.3-125 nmol/L

Not for pediatric patients

Specimen Requirements


A gold-top serum gel tube (s) or a plain, red-top tube(s) is also acceptable. Spin down and send 1 mL refrigerated 

Also Acceptable

Draw blood in a mint green-top (heparin) gel tube(s). Spin down and send 1 mL of heparinized plasma refrigerated. 


Specimen Stability Information

Specimen Type Temperature Time
Serum or plasma Refrigerated 7 days
  Ambient  5 days
  Frozen  12 months

Day(s) Test Set Up

Monday-Friday Day and Evening shift

Saturday and Sunday day shift

Performing Laboratory

OhioHealth Laboratory Services-RMH Special Testing