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Test Code LAB90460 von Willebrand Panel

Reporting Title

vWF Profile

Methodology

Profile Information:
Unit Codes  Published Name Available Separately
     
LAB325

Activated Partial Thromboplastin Time (APTT)

 Yes 
LAB306 Factor VIII Assay Yes
LAB301 Platelet Count Yes

LAB318

 Platelet Function Assay (PFA) Yes
    LAB90129 Platelet Morphology Yes
LAB320 Protime (PT) Yes
LAB335 Ristocetin Cofactor Yes
    LAB90148 von Willebrand Factor Antigen Yes

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

LAB90148 “von Willebrand Factor Multimer Analysis, Plasma” should be ordered when classification of von Willebrand disease is necessary.

This risk profile should be ordered on patients presenting with a history suggestive of von Willebrand’s disease.

Performing Laboratory

OhioHealth Laboratory Services-RMH Core Coagulation

Specimen Requirements

Citrated whole blood or plasma and EDTA whole blood are required for this test.

 

Blood for APTT, Factor VIII Assay, PT, and Ristocetin Cofactor

 

Riverside Inpatient or Riverside Campus draw sites:

Testing must be performed within 4 hours of draw if submitting unprocessed whole blood.

Draw 6 full, light blue-top (citrate) tubes; and send citrated whole blood. Invert several times to mix blood. Do not centrifuge. Forward unprocessed whole blood promptly at ambient temperature only. Do not refrigerate. Specimen cannot be frozen.

 

Outpatient/Outreach Clients

Plasma-Frozen

Draw 10 full, light blue-top (citrate) tubes, aliquot plasma, double spin and aliquot again. Send plasma.

Note:  1. Gross hemolysis, lipemia, or icteric specimen may affect results.

2. Label specimens appropriately (citrated whole blood for APTT, Factor VIII activity, PFA, PT, and ristocetin).

 

Blood for Platelet Count and Platelet Morphology

Draw a full, lavender-top (EDTA) tube; and send EDTA whole blood. Invert several times to mix blood. Do not centrifuge. Forward unprocessed whole blood promptly at ambient temperature if received within 24 hours. Specimens stored refrigerated 2-8 degrees are acceptable for up to 48 hours. Specimens canot be frozen.

Note:  Label specimen appropriately (EDTA whole blood for platelet count and morphology).

 

von Willebrand Factor Antigen

See LAB90148 “von Willebrand Factor Antigen, Plasma” for specimen required.

 

PFA

See LAB318 PFA for specimen required

Specimen Transport Temperature

Ambient/Refrigerate Yes/Frozen NO

Reference Values

VON WILLEBRAND FACTOR ANTIGEN

See LAB90148 “von Willebrand Factor Antigen, Plasma” for reference values.

See individual test listings for all other tests.

Day(s) Test Set Up

APTT, Platelet Count, PFA, PT:  Monday through Sunday

Factor VIII Activity, Platelet Morphology, Ristocetin Cofactor:  Monday through Friday

von Willebrand Factor Antigen:  See #45593 “von Willebrand Factor Antigen, Plasma”

Test Classification and CPT Coding

“von Willebrand Factor Antigen”

See #45593 “von Willebrand Factor Antigen, Plasma”

85008 - platelet morphology

85049 - platelet count

85240 - factor VIII

85245 - ristocetin

85576 - PFA

85610 - PT

85730 - APTT

85576 - PFA-ADP (if appropriate)