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Test Code RFPN Rheumatoid Factor Panel, Serum


Additional Testing Requirements


Rheumatoid factor (RF) IgA and RF IgM should be tested in combination with CCP / Cyclic Citrullinated Peptide Antibodies, IgG, Serum; or following positive or equivocal results for either RHUT / Rheumatoid Factor, Serum; or RAPAN / Rheumatoid Arthritis Panel, Serum.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Useful For

Evaluating patients at-risk of rheumatoid arthritis (RA) or features of inflammatory arthritis

 

Differentiating the antibody isotype profile in patients positive for rheumatoid factor (RF)

 

Aid in the risk stratification of RF-seropositive patients with RA

Profile Information

Test ID Reporting Name Available Separately Always Performed
RFA Rheumatoid Factor IgA, S No Yes
RFM Rheumatoid Factor IgM, S No Yes

Method Name

Chemiluminescent Immunoassay

Reporting Name

Rheumatoid Factor Panel, S

Specimen Type

Serum

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  48 hours

Reference Values

RHEUMATOID FACTOR, IgA

Negative: <20 CU

Positive: ≥20 CU

Reference values apply to all ages.

 

RHEUMATOID FACTOR, IgM

Negative: <5.0 IU/mL

Positive: ≥5.0 IU/mL

Reference values apply to all ages.

Day(s) Performed

Wednesday

Report Available

2 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86431 x2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RFPN Rheumatoid Factor Panel, S 106053-2

 

Result ID Test Result Name Result LOINC Value
RFM Rheumatoid Factor IgM, S 9338-5
RFA Rheumatoid Factor IgA, S 33313-8